mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.

نویسندگان

  • Mathieu Laplante
  • David M Sabatini
چکیده

Correction for “mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis,” by Mathieu Laplante and David Sabatini, which appeared in issue 8, February 23, 2010, of Proc Natl Acad Sci USA (107:3281–3282; first published February 18, 2010; 10.1073/pnas.1000323107). The authors note that, on page 3281, left column, second paragraph, the fourth sentence is incorrect in part. “In addition to promoting glucose uptake by allowing the translocation of the glucose transporter-4 to the plasma membrane, the activation of Akt by insulin stimulates the phosphorylation of the Forkhead box O1 (FoxO1), a transcription factor that controls gluconeogenesis (5)” should read “The activation of Akt by insulin stimulates the phosphorylation of the Forkhead box O1 (FoxO1), a transcription factor that controls gluconeogenesis (5).” The authors also note that Fig. 1 appeared incorrectly. The corrected figure and its legend appear below.

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عنوان ژورنال:
  • Proceedings of the National Academy of Sciences of the United States of America

دوره 107 8  شماره 

صفحات  -

تاریخ انتشار 2010